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Regular price $52.50 USD
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Decreased to absent levels occur more with intravascular than extravascular hemolysis: haptoglobin binds hemoglobin, and carries it to the reticuloendothelial system. Thus, haptoglobin is useful in work-up for hemolytic states. It is low in the megaloblastic anemias, which have a hemolytic component. It is decreased in infectious mononucleosis. Decreases can occur with hematoma or tissue hemorrhage. Haptoglobin can be low with liver disease. Congenital absence occurs (small fraction of certain ethnic populations have ahaptoglobinemia, absence of detectable haptoglobin). Frequently elevated as an acute phase reactant, in inflammatory disorders (eg, collagen diseases, infections, tissue destruction, and with advanced malignant neoplasms)

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