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Triiodothyronine (T3), Free, Dialysis and LC/MS-MS (Endocrine Sciences)
Triiodothyronine (T3), Free, Dialysis and LC/MS-MS (Endocrine Sciences)
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Additional Information
Direct measurement of FT3 by equilibrium dialysis, high-pressure liquid chromatography, and tandem mass spectrometry (ED-HPLC/MS-MS) provides enhanced accuracy over commonly used analog (automated) methods and is not affected by clinical conditions that impact protein binding capacity. Examples of clinical conditions in which the FT3 by dialysis and MS/MS method may be preferred include congenital absence of thyroxine-binding protein (TBG); pregnancy; administration of oral contraceptives or hormone therapy; administration of atypical antipsychotic medications; malignancy or other critical illnesses.
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